Originally published by 2 Minute Medicine^® (view original article). Reused on AccessMedicine with permission.

1. The Critical-Care Pain Observation Tool (CPOT) showed strong correlations with other validated pain observation tools in pediatric patients

Evidence Rating Level: 3 (Average)

The Critical-Care Pain Observation Tool (CPOT), a behavioral pain assessment scale validated in adults, was evaluated for use in critically ill pediatric patients, particularly in mixed-age intensive care units where a single, versatile tool is beneficial. This prospective observational study included 91 children (165 assessments) aged 0–18 years in an open pediatric ICU. CPOT scores were compared with the FLACC scale and an observational Visual Analog Scale (VAS obs) to assess criterion and construct validity. The CPOT showed strong correlations with FLACC (ρ = 0.84) and VAS obs (ρ = 0.87), with especially high agreement among intubated and non-intubated patients. A CPOT cutoff score of ≥3 demonstrated excellent diagnostic performance (AUC = 0.98, sensitivity 100%, specificity 96.7%). CPOT scores significantly increased during painful medical interventions (p < 0.01), supporting its responsiveness to procedural pain. Inter-rater reliability was high (weighted κ = 0.89), confirming consistency across observers. While further validation is needed in larger, more diverse populations and among patients with neurological impairments, these findings suggest that CPOT is a valid, reliable, and practical tool for assessing pain in critically ill pediatric patients and may facilitate standardized pain management across age groups and care settings.

Click to read the study in PLOSONE

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