Print Get Citation Citation Disclaimer: These citations have been automatically generated based on the information we have and it may not be 100% accurate. Please consult the latest official manual style if you have any questions regarding the format accuracy. AMA Citation Lennon J, Chan A. Lennon J, & Chan A Lennon, Jack, and Alex Chan. COVID-19 infection in late pregnancy associated with adverse birth outcomes. 2 Minute Medicine, 29 October 2020. McGraw-Hill, 2020. AccessMedicine. https://accessmedicine.mhmedical.com/updatesContent.aspx?gbosid=554677§ionid=251480744APA Citation Lennon J, Chan A. Lennon J, & Chan A Lennon, Jack, and Alex Chan. (2020). Covid-19 infection in late pregnancy associated with adverse birth outcomes. (2020). 2 minute medicine. McGraw-Hill. https://accessmedicine.mhmedical.com/updatesContent.aspx?gbosid=554677§ionid=251480744.MLA Citation Lennon J, Chan A. Lennon J, & Chan A Lennon, Jack, and Alex Chan. "COVID-19 infection in late pregnancy associated with adverse birth outcomes." 2 Minute Medicine McGraw-Hill, 2020, https://accessmedicine.mhmedical.com/updatesContent.aspx?gbosid=554677§ionid=251480744. Download citation file: RIS (Zotero) EndNote BibTex Medlars ProCite RefWorks Reference Manager Mendeley © Copyright Clip Full Chapter Figures Only Tables Only Videos Only Supplementary Content COVID-19 infection in late pregnancy associated with adverse birth outcomes by Jack Lennon, Alex Chan Listen +Originally published by 2 Minute Medicine® (view original article). Reused on AccessMedicine with permission. +1. COVID-19 infection in late pregnancy was associated with adverse birth outcomes, such as cesarean section delivery and iatrogenic preterm birth. +2. Limited evidence was found for maternal-fetal vertical transmission of SARS-CoV-2. +Evidence Rating Level: 3 (Average) +Coronavirus disease 2019 (COVID-19) is an ongoing concern in the healthcare sector. However, little is currently known about the transmission of COVID-19 during pregnancy. This retrospective cohort study used the Maternal and Child Health Information System of Wuhan, China, aiming to investigate the association between maternal COVID-19 and adverse birth outcomes. Included in analyses were all pregnant women with singleton, live births occurring between January 13, 2020 and March 18, 2020. A total of 11,078 pregnant women were included in analyses, with 65 (0.587%) confirmed cases of COVID-19. Roughly 78% of COVID-19– and 83% of COVID-19+ women were between the ages of 25 and 34 years. Of the positive cases, 65% had a bachelor’s degree or higher. Compared to COVID-19- mothers, those with COVID-19 had 3.34 greater odds of preterm birth (adjusted OR = 3.34, 95% CI 1.60 to 7.00) and 3.63 higher odds of cesarean section birth (adjusted OR = 3.63, 95% CI 1.95 to 6.76). Mothers with COVID-19 also demonstrated greater odds for preterm birth with cesarean section delivery (adjusted OR = 3.71, 95% CI 1.70 to 8.03). No statistical differences between groups were found in low birth weight, premature rupture of membrane, or neonatal asphyxia. Further, none of the newborns born to mothers with COVID-19 were positive for SARS-CoV-2, nor did they have abnormal CT findings. Symptoms occurred in four children, one experiencing diarrhea and three experiencing fever. Overall, COVID-19 among pregnant women appears to increase the odds of adverse birth outcomes. However, maternal-fetal transmission of the virus does not seem to be a concern based on this study. +Click to read the study in BMC Medicine +©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.