Print Get Citation Citation Disclaimer: These citations have been automatically generated based on the information we have and it may not be 100% accurate. Please consult the latest official manual style if you have any questions regarding the format accuracy. AMA Citation Lau D, Chan A. Lau D, & Chan A Lau, Davy, and Alex Chan. Temporal estimates of case-fatality rate for COVID-19 outbreaks in Canada and the United States. 2 Minute Medicine, 2 July 2020. McGraw-Hill, 2020. AccessMedicine. https://accessmedicine.mhmedical.com/updatesContent.aspx?gbosid=550803§ionid=248404978APA Citation Lau D, Chan A. Lau D, & Chan A Lau, Davy, and Alex Chan. (2020). Temporal estimates of case-fatality rate for covid-19 outbreaks in canada and the united states. (2020). 2 minute medicine. McGraw-Hill. https://accessmedicine.mhmedical.com/updatesContent.aspx?gbosid=550803§ionid=248404978.MLA Citation Lau D, Chan A. Lau D, & Chan A Lau, Davy, and Alex Chan. "Temporal estimates of case-fatality rate for COVID-19 outbreaks in Canada and the United States." 2 Minute Medicine McGraw-Hill, 2020, https://accessmedicine.mhmedical.com/updatesContent.aspx?gbosid=550803§ionid=248404978. Download citation file: RIS (Zotero) EndNote BibTex Medlars ProCite RefWorks Reference Manager Mendeley © Copyright Clip Full Chapter Figures Only Tables Only Videos Only Supplementary Content Top Temporal estimates of case-fatality rate for COVID-19 outbreaks in Canada and the United States by Davy Lau, Alex Chan Listen +Originally published by 2 Minute Medicine® (view original article). Reused on AccessMedicine with permission. +1. Covid-19 case fatality estimated to be 1.6% in Canada and 1.8% in the USA +Evidence Rating: 2 (Good) +Covid-19 has disproportionately affected different areas of the world, not just in the number of cases, but also in the case-fatality rate (CFR): the percentage of deaths in comparison to the number of cases. For instance, estimated CFR values have varied from 0.4% in China to 31.4% in northwest Italy. But the estimation of CFR is confounded by two main factors. The first is the delay between contracting Covid-19 and death: When CFR is calculated at a certain point in time, the deaths resulting from currently active cases cannot be taken into account. The second factor is the underreporting of Covid-19 cases, due to lack of testing and asymptomatic individuals. This retrospective cohort study adjusted for these factors and estimated the CFR for Covid-19 in Canada and the USA, based on data on daily incidence of confirmed COVID-19 cases collected from Jan. 31 to Apr. 22, 2020. The CFR for Canada was 1.6% (95% credible interval of 0.7-3.1%) and the CFR for the USA was 1.8% (95% credible interval of 0.8-3.6%). These estimates are under the assumption that reporting rates for Covid-19 are under 50% in both countries. Overall, this principle of accounting for onset to death lag time and the underreporting of cases is important for future CFR estimates in specific regions, to provide a better understanding of the virulence of the SARS-CoV-2. +Click to read the study in CMAJ +©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.