Print Get Citation Citation Disclaimer: These citations have been automatically generated based on the information we have and it may not be 100% accurate. Please consult the latest official manual style if you have any questions regarding the format accuracy. AMA Citation Lennon J, Shah R. Lennon J, & Shah R Lennon, Jack, and Ravi Shah. Bypass grafting versus stenting for patients with severely reduced ejection fraction. 2 Minute Medicine, 28 April 2020. McGraw-Hill, 2020. AccessMedicine. https://accessmedicine.mhmedical.com/updatesContent.aspx?gbosid=548085§ionid=245817345APA Citation Lennon J, Shah R. Lennon J, & Shah R Lennon, Jack, and Ravi Shah. (2020). Bypass grafting versus stenting for patients with severely reduced ejection fraction. (2020). 2 minute medicine. McGraw-Hill. https://accessmedicine.mhmedical.com/updatesContent.aspx?gbosid=548085§ionid=245817345.MLA Citation Lennon J, Shah R. Lennon J, & Shah R Lennon, Jack, and Ravi Shah. "Bypass grafting versus stenting for patients with severely reduced ejection fraction." 2 Minute Medicine McGraw-Hill, 2020, https://accessmedicine.mhmedical.com/updatesContent.aspx?gbosid=548085§ionid=245817345. Download citation file: RIS (Zotero) EndNote BibTex Medlars ProCite RefWorks Reference Manager Mendeley © Copyright Clip Full Chapter Figures Only Tables Only Videos Only Supplementary Content Top Bypass grafting versus stenting for patients with severely reduced ejection fraction by Jack Lennon, Ravi Shah Listen +Originally published by 2 Minute Medicine® (view original article). Reused on AccessMedicine with permission. +1. Patients with severely reduced left ventricular ejection fraction with left main, left anterior descending, or multivessel disease who underwent percutaneous coronary intervention demonstrated higher rates of mortality and major adverse cardiovascular events compared to those who underwent coronary artery bypass grafting. +Evidence Rating Level: 2 (Good) +There is insufficient evidence in the literature on outcomes of revascularization strategies for patients with severely reduced left ventricular ejection fraction (LVEF). This retrospective cohort study of patients in Ontario, Canada sought to determine whether or not outcomes differ between with severely reduced LVEF with left main coronary artery, left anterior descending artery, or multivessel disease who undergo percutaneous coronary intervention (PCI) and those who undergo coronary artery bypass grafting (CABG), including all-cause mortality and death from major adverse cardiovascular events (MACE). Data from 12,113 patients across both the PCI (mean [SD] age = 64.8 [11.0] years, 27.5% female) and CABG (mean [SD] age = 65.6 [9.7] years, 17.1% female) groups were utilized. Patients were propensity score-matched, resulting in 2,397 patients from each group with a median follow-up time of 5.2 years (IQR 5.0 to 5.3). Compared to CABG, researchers found that patients who underwent PCI demonstrated significantly greater mortality rates (HR 1.6, 05% CI 1.3 to 1.7), cardiovascular disease-related death (HR 1.4, 95% CI 1.1 to 1.6), subsequent revascularization (HR 3.7, 95% CI 3.2 to 4.3), MACE (HR 2.0, 95% CI 1.9 to 2.2), and hospitalization for either heart failure (HR 1.5, 95% CI 1.3 to 1.6), heart failure (HR 1.5, 95% CI 1.3 to 1.6), or myocardial infarction (HR 3.2, 95% CI 2.6 to 3.8). Overall, these findings suggest a need to strongly consider interventions for patients with severely reduced LVEF due to the elevated risks of mortality and MACE associated with PCI. +Click to read the study in JAMA Cardiology +©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.