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Alpha 2-adrenergic receptor agonist, centrally acting
Mitigation of opioid withdrawal symptoms; to facilitate abrupt opioid discontinuation
Clonidine, dexmedetomidine, guanfacine, tizanidine
Chapter 8. Neurotransmission: The Autonomic and Somatic Motor Nervous Systems > Alpha Adrenergic Receptors
Chapter 12. Adrenergic Agonists and Antagonists > α2-Selective Adrenergic Receptor Agonists
Chapter 24. Drug Use Disorders and Addiction > Pharmacological Interventions
eChapter 2018: The Goodman & Gilman Year in Review New and Noteworthy FDA Approvals