RT Book, Section
A1 Trevor, Anthony J.
A1 Katzung, Bertram G.
A1 Kruidering-Hall, Marieke
SR Print(0)
ID 1123462252
T1 Pancreatic Hormones, Antidiabetic Agents, & Glucagon
T2 Katzung & Trevor's Pharmacology: Examination & Board Review, 11e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071826358
LK accessmedicine.mhmedical.com/content.aspx?aid=1123462252
RD 2020/02/22
AB In  the  endocrine  pancreas,  the  islets  of  Langerhans  contain  at  least  4  types  of  endocrine  cells,  including  A  (alpha,  glucagon  producing),  B  (beta,  insulin,  and  amylin  producing),  D  (delta,  somatostatin  producing),  and  F  (pancreatic  polypeptide  producing).  Of  these,  the  B  (insulin-producing)  cells  are  the  most  numerous.The  most  common  pancreatic  disease  requiring  pharmacologic  therapy  is  diabetes  mellitus,  a  deficiency  of  insulin  production  or  effect.  Diabetes  is  treated  with  several  parenteral  formulations  of  insulin  and  oral  or  parenteral  noninsulin  antidiabetic  agents.  Glucagon,  a  hormone  that  affects  the  liver,  cardiovascular  system,  and  gastrointestinal  tract,  can  be  used  to  treat  severe  hypoglycemia.