RT Book, Section A1 Trevor, Anthony J. A1 Katzung, Bertram G. A1 Kruidering-Hall, Marieke SR Print(0) ID 1123462252 T1 Pancreatic Hormones, Antidiabetic Agents, & Glucagon T2 Katzung & Trevor's Pharmacology: Examination & Board Review, 11e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071826358 LK accessmedicine.mhmedical.com/content.aspx?aid=1123462252 RD 2022/05/22 AB In the endocrine pancreas, the islets of Langerhans contain at least 4 types of endocrine cells, including A (alpha, glucagon producing), B (beta, insulin, and amylin producing), D (delta, somatostatin producing), and F (pancreatic polypeptide producing). Of these, the B (insulin-producing) cells are the most numerous.The most common pancreatic disease requiring pharmacologic therapy is diabetes mellitus, a deficiency of insulin production or effect. Diabetes is treated with several parenteral formulations of insulin and oral or parenteral noninsulin antidiabetic agents. Glucagon, a hormone that affects the liver, cardiovascular system, and gastrointestinal tract, can be used to treat severe hypoglycemia.