RT Book, Section
A1 Carroll, Karen C.
A1 Hobden, Jeffery A.
A1 Miller, Steve
A1 Morse, Stephen A.
A1 Mietzner, Timothy A.
A1 Detrick, Barbara
A1 Mitchell, Thomas G.
A1 McKerrow, James H.
A1 Sakanari, Judy A.
SR Print(0)
ID 1114737569
T1 Orthomyxoviruses (Influenza Viruses)
T2 Jawetz, Melnick, & Adelberg’s Medical Microbiology, 27e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071824989
LK accessmedicine.mhmedical.com/content.aspx?aid=1114737569
RD 2024/04/23
AB Respiratory  illnesses  are  responsible  for  more  than  half  of  all  acute  illnesses  each  year  in  the  United  States.  The  Orthomyxoviridae  (influenza  viruses)  are  a  major  determinant  of  morbidity  and  mortality  caused  by  respiratory  disease,  and  outbreaks  of  infection  sometimes  occur  in  worldwide  epidemics.  Influenza  has  been  responsible  for  millions  of  deaths  worldwide.  Mutability  and  high  frequency  of  genetic  reassortment  and  resultant  antigenic  changes  in  the  viral  surface  glycoproteins  make  influenza  viruses  formidable  challenges  for  control  efforts.  Influenza  type  A  is  antigenically  highly  variable  and  is  responsible  for  most  cases  of  epidemic  influenza.  Influenza  type  B  may  exhibit  antigenic  changes  and  sometimes  causes  epidemics.  Influenza  type  C  is  antigenically  stable  and  causes  only  mild  illness  in  immunocompetent  individuals.