RT Book, Section
A1 Carroll, Karen C.
A1 Hobden, Jeffery A.
A1 Miller, Steve
A1 Morse, Stephen A.
A1 Mietzner, Timothy A.
A1 Detrick, Barbara
A1 Mitchell, Thomas G.
A1 McKerrow, James H.
A1 Sakanari, Judy A.
SR Print(0)
ID 1114733298
T1 Normal Human Microbiota
T2 Jawetz, Melnick, & Adelberg’s Medical Microbiology, 27e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071824989
LK accessmedicine.mhmedical.com/content.aspx?aid=1114733298
RD 2024/04/25
AB The  term  “normal  microbial  flora”  denotes  the  population  of  microorganisms  that  inhabit  the  skin  and  mucous  membranes  of  healthy  normal  persons.  The  microorganisms  that  live  inside  and  on  humans  (now  referred  to  as  the  normal  microbiota)  are  estimated  to  outnumber  human  somatic  and  germ  cells  by  a  factor  of  10.  The  genomes  of  these  microbial  symbionts  are  collectively  defined  as  the  microbiome.  Research  has  shown  that  the  “normal  microbiota”  provides  a  first  line  of  defense  against  microbial  pathogens,  assist  in  digestion,  play  a  role  in  toxin  degradation,  and  contribute  to  maturation  of  the  immune  system.  Shifts  in  the  normal  microbiota  or  stimulation  of  inflammation  by  these  commensals  may  cause  diseases  such  as  bacterial  vaginosis,  periodontitis,  and  inflammatory  bowel  disease.