RT Book, Section A1 Carroll, Karen C. A1 Hobden, Jeffery A. A1 Miller, Steve A1 Morse, Stephen A. A1 Mietzner, Timothy A. A1 Detrick, Barbara A1 Mitchell, Thomas G. A1 McKerrow, James H. A1 Sakanari, Judy A. SR Print(0) ID 1114732735 T1 Microbial Metabolism T2 Jawetz, Melnick, & Adelberg’s Medical Microbiology, 27e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071824989 LK accessmedicine.mhmedical.com/content.aspx?aid=1114732735 RD 2024/04/19 AB Microbial growth requires the polymerization of biochemical building blocks into proteins, nucleic acids, polysaccharides, and lipids. The building blocks must come preformed in the growth medium or must be synthesized by the growing cells. Additional biosynthetic demands are placed by the requirement for coenzymes that participate in enzymatic catalysis. Biosynthetic polymerization reactions demand the transfer of anhydride bonds from adenosine triphosphate (ATP). Growth demands a source of metabolic energy for the synthesis of anhydride bonds and for the maintenance of transmembrane gradients of ions and metabolites.