RT Book, Section A1 Greenberg, Raymond S. A1 Lackland, Daniel T. A2 Greenberg, Raymond S. SR Print(0) ID 1108590422 T1 Case-Control Studies T2 Medical Epidemiology: Population Health and Effective Health Care, 5e YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-182272-5 LK accessmedicine.mhmedical.com/content.aspx?aid=1108590422 RD 2024/04/19 AB In 1986, Barker and Osmond published a study that examined patterns of death related to coronary heart disease in England and Wales between 1968 and 1978. These investigators found that the death rates in the northern industrial towns were about 20% above the national average. In contrast, the more affluent areas in the rural south and east had heart disease death rates that were 20% below the national average. The pattern of death rates from coronary heart disease among adults paralleled that for infant mortality a half century earlier. One in 10 newborns died in the first year of life in the industrial north compared with one in 20 in the rural south and east.