RT Book, Section A1 Reznik, Scott I. A1 Smythe, W. Roy A2 Grippi, Michael A. A2 Elias, Jack A. A2 Fishman, Jay A. A2 Kotloff, Robert M. A2 Pack, Allan I. A2 Senior, Robert M. A2 Siegel, Mark D. SR Print(0) ID 1122367439 T1 Treatment of Non–Small-Cell Lung Cancer: Surgery T2 Fishman's Pulmonary Diseases and Disorders, 5e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 978-0-07-179672-9 LK accessmedicine.mhmedical.com/content.aspx?aid=1122367439 RD 2024/04/19 AB Lung cancer represents the most common cause of cancer-related death in the world. It was considered a rare disease until the early part of the 20th century. In 1879, lung cancer represented only 1% of cancers identified at autopsy compared to 14% in 1927.1 The famous surgeon, Alton Oschner reported that as a medical student in 1910, he was called to the autopsy suite to see a case of lung cancer, since it was so rare he was likely to never see another case. Seventeen years passed before he saw another case of lung cancer and then he saw 8 cases in 6 months.2 The link between tobacco use and lung cancer has been common knowledge since the surgeon general's report in 1964, and despite that knowledge, the death rate continued to rise in men until 1991 and in women until 2003. The treatment of lung cancer has evolved from a single modality, surgery, to a multimodality approach that calls upon the skills of numerous specialists. Physicians, who diagnose and treat lung cancer, must work together to define the role that surgery plays in the modern management of lung cancer. Surgery, when appropriate remains the cornerstone of therapy, and surgeons play an integral role in the diagnosis and treatment of patients with lung cancer.