RT Book, Section
A1 Martinez, Fernando J.
A2 Grippi, Michael A.
A2 Elias, Jack A.
A2 Fishman, Jay A.
A2 Kotloff, Robert M.
A2 Pack, Allan I.
A2 Senior, Robert M.
A2 Siegel, Mark D.
SR Print(0)
ID 1122360256
T1 Bullous Disease of the Lung
T2 Fishman's Pulmonary Diseases and Disorders, 5e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-179672-9
LK accessmedicine.mhmedical.com/content.aspx?aid=1122360256
RD 2020/09/26
AB A  bulla  is  an  air-containing  space  within  the  lung  parenchyma  that  arises  from  destruction,  dilatation,  and  confluence  of  airspaces  distal  to  terminal  bronchioles  and  is  larger  than  1  cm  in  diameter  (Fig.  52-1).1  Its  walls  are  composed  of  attenuated  and  compressed  parenchyma.  Bullae  occur  in  various  clinical  contexts:  (1)  with  emphysema  (“bullous  emphysema”);  (2)  with  pulmonary  fibrosis,  as  in  the  late  stages  of  sarcoidosis  or  complicated  pneumoconiosis;  (3)  in  so-called  “vanishing  lung,”  in  which  the  parenchyma  is  rapidly  replaced  by  multiple  bullae;  and  (4)  in  lungs  that  are  otherwise  normal  (“bullous  lung  disease”)  and,  therefore,  likely  secondary  to  a  mechanism  different  from  that  of  bullae  occurring  in  conjunction  with  emphysema  (Table  52-1).2,3