RT Book, Section
A1 Bell, Matthew C.
A1 Busse, William W.
A2 Grippi, Michael A.
A2 Elias, Jack A.
A2 Fishman, Jay A.
A2 Kotloff, Robert M.
A2 Pack, Allan I.
A2 Senior, Robert M.
A2 Siegel, Mark D.
SR Print(0)
ID 1122359199
T1 The Biology of Asthma
T2 Fishman's Pulmonary Diseases and Disorders, 5e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-179672-9
LK accessmedicine.mhmedical.com/content.aspx?aid=1122359199
RD 2024/04/25
AB Asthma  is  characterized  by  recurrent  attacks  of  breathlessness  and  wheezing,  which  vary  in  severity  and  frequency  from  person  to  person.1  More  than  18  million  adults  and  7  million  children  are  affected  in  the  United  States  alone,  making  asthma  one  of  the  most  common  chronic  diseases  in  this  country.2  Attempts  to  elucidate  the  underlying  pathophysiology  of  the  disease  have  led  to  the  realization  that  asthma  truly  is  a  protean  disease  with  various  cell  types  and  mechanisms  playing  variable  but  important  roles  in  each  patient.  This  degree  of  mechanistic  variation  explains  the  numerous  phenotypes  of  this  disease  as  well  as  the  differences  in  response  to  treatment.