RT Book, Section A1 Shary, Thomas M. A1 Chapman, Emily A. A1 Herrmann, Virginia M. A2 Doherty, Gerard M. SR Print(0) ID 1105484718 T1 Surgical Metabolism & Nutrition T2 CURRENT Diagnosis & Treatment: Surgery, 14e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071792110 LK accessmedicine.mhmedical.com/content.aspx?aid=1105484718 RD 2024/04/18 AB The effects of malnutrition on the surgical patient are well characterized in the literature but are often overlooked in the clinical arena. Between 30% and 50% of hospitalized patients are malnourished. Protein-calorie malnutrition produces a reduction in lean muscle mass, alterations in respiratory mechanics, impaired immune function, and intestinal atrophy. These changes result in diminished wound healing, predisposition to infection, and increased postoperative morbidity. Although most healthy individuals can tolerate up to 7 days of starvation (with adequate glucose and fluid replacement), those subjected to major trauma, the physiologic stress of surgery, sepsis, or cancer-related cachexia require earlier nutritional intervention. Methods to identify those at greatest need for supplemental nutrition and to adequately address their needs are discussed in this chapter.