RT Book, Section A1 Galgon, Healther A1 Russel, Jacqueline A1 Asante, Kwame A1 Maitin, Ian B. A2 Maitin, Ian B. A2 Cruz, Ernesto SR Print(0) ID 1105129152 T1 Neuropathy T2 CURRENT Diagnosis & Treatment: Physical Medicine & Rehabilitation YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071793292 LK accessmedicine.mhmedical.com/content.aspx?aid=1105129152 RD 2024/04/24 AB Diabetes mellitus is the most common cause of peripheral neuropathy worldwide. In clinical practice, the two conditions often seem to be synonymous: more than half of all patients with diabetes have neuropathy, and half the patients with neuropathy have diabetes. Disease-related changes in diabetic individuals with neuropathy cause a wide range of presentations, reflecting acute or chronic symptoms in a variety of anatomic locations, such as skin, nerve root, vasculature, and autonomic nervous system. The discussion that follows focuses on three characteristic presentations: distal symmetric polyneuropathy, diabetic amyotrophy, and diabetic autonomic neuropathy. Characteristic features of each are contrasted in Table 17–1. Focal mononeuropathy caused by diabetes produces symptoms similar to those of compressive or entrapment neuropathies, which are discussed at the end of this chapter.