RT Book, Section
A1 LeBlond, Richard F.
A1 Brown, Donald D.
A1 Suneja, Manish
A1 Szot, Joseph F.
SR Print(0)
ID 1139369343
T1 The Female Genitalia and Reproductive System
T2 DeGowin’s Diagnostic Examination, 10e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-181447-8
LK accessmedicine.mhmedical.com/content.aspx?aid=1139369343
RD 2024/04/18
AB Male  and  female  external  genitalia,  arising  from  identical  embryologic  anlage,  differentiate  depending  on  the  presence  or  absence  of  testosterone.  Lack  of  the  SRY  gene  (typically  found  on  the  Y  chromosome)  leads  to  development  of  ovaries,  with  subsequent  maturation  of  female  sex  organs.  The  labia  majora  is  a  cognate  of  the  scrotum  and  the  clitoris  and  penis  are  similarly  derived.  Ambiguous  genitalia  occur  when  development  and  maturation  occurs  with  a  mixed  genetic  substrate  or  hormonal  environment.