RT Book, Section A1 Aster, Jon C. A1 DeAngelo, Daniel J. A2 Bunn, H. Franklin A2 Aster, Jon C. SR Print(0) ID 1104131741 T1 Acute Leukemias T2 Pathophysiology of Blood Disorders YR 2011 FD 2011 PB McGraw-Hill Medical PP New York, NY SN 9780071713788 LK accessmedicine.mhmedical.com/content.aspx?aid=1104131741 RD 2024/10/05 AB LEARNING OBJECTIVESAfter studying this chapter you should understand:The pathogenic role of mutations in genes encoding transcription factors and signaling molecules in acute leukemia.The diagnostic and prognostic role of immunophenotyping, cytogenetics, and molecular genetics in acute leukemia.The general approach to treatment of patients with acute leukemia and the associated short-term complications.The unique role of "differentiating" agents in the treatment of acute promyelocytic leukemia.