RT Book, Section A1 Bunn, H. Franklin A2 Bunn, H. Franklin A2 Aster, Jon C. SR Print(0) ID 1104130828 T1 Overview of the Anemias T2 Pathophysiology of Blood Disorders YR 2011 FD 2011 PB McGraw-Hill Medical PP New York, NY SN 9780071713788 LK accessmedicine.mhmedical.com/content.aspx?aid=1104130828 RD 2024/10/08 AB LEARNING OBJECTIVESAfter studying this chapter you should:Understand how anemia impacts oxygen transport and the ways in which anemic patients compensate for decreased oxygen-carrying capacity.Develop a coherent approach to the clinical and laboratory evaluation of patients with anemia.Understand and use classification of anemia based on production versus destruction and on red cell size (mean cell volume).Be able to explain the phenomenon of ineffective erythropoiesis—its diagnosis and role in pathogenesis.Understand the process by which red cells are broken down, the catabolism of heme in macrophages, and the transport of bilirubin in the plasma and its conjugation in the liver.