RT Book, Section A1 Durrani, Timur S. A1 Benowitz, Neal L. A2 LaDou, Joseph A2 Harrison, Robert J. SR Print(0) ID 1104104029 T1 Cardiovascular Toxicology T2 CURRENT Diagnosis & Treatment: Occupational & Environmental Medicine, 5e YR 2013 FD 2013 PB McGraw-Hill Education PP New York, NY SN 9780071808156 LK accessmedicine.mhmedical.com/content.aspx?aid=1104104029 RD 2024/03/29 AB Heart disease and stroke cause the majority of deaths in the United States. The major risk factors for coronary heart disease—family history, hypertension, diabetes, lipid abnormalities, and cigarette smoking—explain only a minority of the cases. Other factors, such as stress and exposure to occupational or environmental toxic agents, are believed to contribute to the development of heart disease, although the magnitude of the risk is unknown.