RT Book, Section
A1 Newlin, Anna
A1 Hulick, Peter
A2 Murray, Michael F.
A2 Babyatsky, Mark W.
A2 Giovanni, Monica A.
A2 Alkuraya, Fowzan S.
A2 Stewart, Douglas R.
SR Print(0)
ID 1102700862
T1 Renal Cell Carcinoma
T2 Clinical Genomics: Practical Applications in Adult Patient Care
YR 2014
FD 2014
PB McGraw-Hill Education
PP New York, NY
SN 9780071622448
LK accessmedicine.mhmedical.com/content.aspx?aid=1102700862
RD 2024/04/20
AB Disease  summary:Approximately  50,000  new  cases  of  renal  cell  carcinoma  (RCC)  are  diagnosed  each  year.RCCs  are  adenocarcinomas  derived  from  renal  tubular  epithelium.  Renal  carinoma  is  comprised  of  several  different  types  of  cancer,  each  with  a  different  histologic  type,  with  a  different  clinical  course,  responding  differently  to  therapy,  and  caused  by  different  genes.Histologically,  there  are  five  subtypes:  Conventional  (clear  cell)  (70%-80%)Chromophile  (papillary)  (10%-15%).  Papillary  is  further  classified  into  type  1  (5%)  and  type  2  (10%  of  cases)  based  on  further  genetic  alterations,  histologic,  and  genetic  criteriaChromophobe  (3%-5%)Collecting  duct  (1%)Unclassified  (1%)