RT Book, Section
A1 Barnes, Carl
A1 Taylor, Matthew RG
A2 Murray, Michael F.
A2 Babyatsky, Mark W.
A2 Giovanni, Monica A.
A2 Alkuraya, Fowzan S.
A2 Stewart, Douglas R.
SR Print(0)
ID 1102699245
T1 Arrhythmogenic Right Ventricular Cardiomyopathy
T2 Clinical Genomics: Practical Applications in Adult Patient Care
YR 2014
FD 2014
PB McGraw-Hill Education
PP New York, NY
SN 9780071622448
LK accessmedicine.mhmedical.com/content.aspx?aid=1102699245
RD 2024/10/05
AB Disease  summary:Arrhythmogenic  right  ventricular  cardiomyopathy  (ARVC),  formerly  referred  to  as  arrhythmogenic  right  ventricular  dysplasia  (ARVD),  is  a  heart  muscle  disease  predominantly  affecting  the  right  ventricle.Pathologically,  the  central  feature  is  a  progressive  replacement  of  right  ventricular  myocardium  with  fibrofatty  tissue.Clinically,  affected  individuals  present  with  palpitations,  syncope,  or  sudden  death  as  a  result  of  ventricular  arrhythmias,  such  as  ventricular  tachycardia  or  fibrillation,  with  symptomatic  heart  failure  usually  only  in  later  stages.While  the  majority  of  patients  do  not  present  with  sudden  cardiac  death,  ARVC  may  account  for  10%  to  20%  of  sudden  cardiac  death  in  individuals  younger  than  age  35.The  prevalence  of  ARVC  is  estimated  to  be  1  case  per  1000  to  5000  of  the  general  population.