RT Book, Section
A1 Vanasse, Gary J.
A2 Williams, Brie A.
A2 Chang, Anna
A2 Ahalt, Cyrus
A2 Chen, Helen
A2 Conant, Rebecca
A2 Landefeld, C. Seth
A2 Ritchie, Christine
A2 Yukawa, Michi
SR Print(0)
ID 1100068320
T1 Anemia
T2 Current Diagnosis & Treatment: Geriatrics, 2e
YR 2014
FD 2014
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-179208-0
LK accessmedicine.mhmedical.com/content.aspx?aid=1100068320
RD 2024/04/16
AB Anemia  is  a  common  condition  in  older  adults  and  is  an  increasingly  recognized  contributor  to  increased  morbidity  and  mortality.  Similar  to  the  younger  adult  anemic  patient,  anemia  in  older  adults  is  most  commonly  defined  according  to  the  1968  World  Health  Organization  (WHO)  criteria  of  a  hemoglobin  (Hgb)  <13  g/dL  in  men  and  <12  g/dL  in  women.  Although  anemia  has  often  been  considered  a  normal  consequence  of  aging,  its  association  with  adverse  clinical  outcomes  merits  a  thorough  evaluation  into  the  underlying  pathophysiology.  Recent  studies  suggest  that  anemia  may  arise  as  a  result  of  accumulated  effects  of  age-related  comorbidities  acting  in  concert  with  poorly  understood  age-specific  changes  in  early  hematopoietic  progenitors,  that  combine  to  influence  erythrocyte  production.  A  greater  understanding  of  the  pathogenesis  of  anemia  in  older  adults  will  likely  have  important  implications  for  the  prevention,  diagnosis,  and  therapy  of  this  common  problem.