RT Book, Section
A1 Ropper, Allan H.
A1 Samuels, Martin A.
A1 Klein, Joshua P.
SR Print(0)
ID 57624842
T1 Chapter 36. Multiple Sclerosis and Other Inflammatory Demyelinating Diseases
T2 Adams and Victor's Principles of Neurology, 10e
YR 2014
FD 2014
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0071794794
LK accessmedicine.mhmedical.com/content.aspx?aid=57624842
RD 2021/04/23
AB It  has  long  been  the  practice  to  set  apart  a  group  of  diseases  of  the  brain  and  spinal  cord  in  which  destruction  of  myelin,  termed  demyelination,  is  a  prominent  feature.  To  define  these  diseases  precisely  is  difficult,  for  the  simple  reason  that  there  is  probably  no  disease  in  which  myelin  destruction  is  the  exclusive  pathologic  change.  The  idea  of  a  demyelinating  disease  is  an  abstraction  that  serves  primarily  to  focus  attention  on  one  of  the  more  striking  and  distinctive  features  of  one  group  of  pathologic  processes.  Another  unifying  feature  of  most  of  these  processes  is  the  participation  of  an  inflammatory  reaction  in  proximity  to  demyelination.  The  most  common  and  important  inflammatory  demyelinating  disease  is  multiple  sclerosis  (MS).