RT Book, Section A1 Wong, Yee Weng A1 Schulman, Kevin A. A2 Lopes, Renato D. A2 Harrington, Robert A. SR Print(0) ID 57835286 T1 Chapter 4. Ethics of Clinical Research: An Overview and Emerging Issues T2 Understanding Clinical Research YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-174678-6 LK accessmedicine.mhmedical.com/content.aspx?aid=57835286 RD 2024/03/28 AB Clinical research has been pivotal in improving human health over the last century. Understanding of human biology and therapeutic innovation are direct results of sound clinical research involving human volunteers. Responsible and careful planning and implementation of research protocols, guided by ethical values and principles, safeguard the very people that the research is intended to benefit. In this chapter, we provide a brief overview of the ethical principles underlying clinical research and the historical context that shapes current standards. We then address practical applications of these principles and explore emerging issues.