RT Book, Section A1 Gensler, Lianne S. A2 Imboden, John B. A2 Hellmann, David B. A2 Stone, John H. SR Print(0) ID 57275398 T1 Chapter 59. Osteonecrosis T2 CURRENT Diagnosis & Treatment: Rheumatology, 3e YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-163805-0 LK accessmedicine.mhmedical.com/content.aspx?aid=57275398 RD 2024/04/19 AB Usually presents with pain upon weight-bearing and motion of the affected joint.The most common site is the femoral head, but the distal femur, ankles, shoulders, wrists and elbows may also be affected.There are many predisposing conditions but glucocorticoid therapy, alcohol abuse, and trauma account for the great majority of cases.MRI has sensitivity for early disease and can detect characteristic abnormalities before radiographic changes are apparent.