RT Book, Section A1 Burns, Christopher A1 Wortmann, Robert L. A2 Imboden, John B. A2 Hellmann, David B. A2 Stone, John H. SR Print(0) ID 57273972 T1 Chapter 44. Gout T2 CURRENT Diagnosis & Treatment: Rheumatology, 3e YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-163805-0 LK accessmedicine.mhmedical.com/content.aspx?aid=57273972 RD 2024/04/24 AB Caused by deposition of uric acid crystals and usually associated with hyperuricemia.Usually begins as an intermittent, acute monoarthritis, especially of the first metatarsophalangeal joint.Over time, attacks become more frequent, less intense, and involve more joints.Diagnosed by demonstrating uric acid crystals in joint fluid.Extra-articular manifestations include tophi and renal stones.Arthritis responds to nonsteroidal anti-inflammatory drugs or colchicine.