RT Book, Section
A1 Seo, Philip
A1 Stone, John H.
A2 Imboden, John B.
A2 Hellmann, David B.
A2 Stone, John H.
SR Print(0)
ID 57273337
T1 Chapter 34. Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome)
T2 CURRENT Diagnosis & Treatment: Rheumatology, 3e
YR 2013
FD 2013
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-163805-0
LK accessmedicine.mhmedical.com/content.aspx?aid=57273337
RD 2024/04/17
AB Asthma,  eosinophilia,  and  systemic  vasculitis  are  the  hallmarks  of  eosinophilic  granulomatosis  with  polyangiitis  (EGPA;  Churg-Strauss  syndrome).Classic  clinical  features  include  the  following:Allergic  rhinitis  and  nasal  polyposis.Reactive  airway  disease.Peripheral  eosinophilia  (10–60%  of  all  circulating  leukocytes).Fleeting  pulmonary  infiltrates  and  occasional  alveolar  hemorrhage.Vasculitic  neuropathy.Congestive  heart  failure.Approximately  50%  of  patients  with  EGPA  have  antineutrophil  cytoplasmic  antibodies  (ANCAs),  usually  with  a  specificity  for  myeloperoxidase  (MPO).