RT Book, Section
A1 Owen, Kelly P.
A2 Olson, Kent R.
SR Print(0)
ID 55977663
T1 Chapter 84. Iodine
T2 Poisoning & Drug Overdose, 6e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-166833-0
LK accessmedicine.mhmedical.com/content.aspx?aid=55977663
RD 2021/04/15
AB The  chief  use  of  iodine  is  for  its  antiseptic  property.  It  is  bactericidal,  sporicidal,  protozoacidal,  cysticidal,  and  virucidal.  Liquid  formulations  of  iodine  are  usually  prepared  in  ethanol  (tincture  of  iodine)  to  increase  solubility  and  concentration.  Lugol  solution  is  5%  iodine  and  10%  iodide  in  water.  Iodoform  is  triiodomethane  (CHI3).  Iodophors  such  as  povidone-iodine  (Betadine)  consist  of  iodine  linked  to  a  large-molecular-weight  molecule.  These  are  usually  less  toxic  owing  to  the  slow  release  of  iodine  from  the  carrier  molecule.  Radioactive  iodine  is  used  in  the  treatment  of  thyroid  cancer.  The  antiarrhythmic  drug  amiodarone  releases  iodine  and  may  cause  either  thyrotoxicosis  or  hypothyroidism  after  prolonged  use.  Iodine  also  is  used  in  the  manufacture  of  dyes  and  photographic  reagents.  Table  salt  is  fortified  with  iodine.