RT Book, Section A1 Provost, Karin A. A1 El-Solh, Ali A. A2 Tobin, Martin J. SR Print(0) ID 57074549 T1 Chapter 41. Complications Associated with Mechanical Ventilation T2 Principles and Practice of Mechanical Ventilation, 3e YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-173626-8 LK accessmedicine.mhmedical.com/content.aspx?aid=57074549 RD 2024/03/28 AB Critically ill patients are at risk of succumbing to their primary disease or the undesired sequelae associated with their therapy. Although frequently lifesaving, the use of positive airway pressure therapy has numerous undesired physiologic and clinical complications. These complications have their origins in the endotracheal or tracheostomy tube, the positive-pressure ventilation (PPV), or from therapies delivered during the care of mechanical ventilation. Other complications may result from coexisting illness or comorbid conditions. Although not commonly recognized as important effects of PPV or positive end-expiratory pressure (PEEP), alterations in organ functions ought to be recognized and addressed accordingly to reduce morbidity and mortality.