RT Book, Section A1 Brochard, Laurent J. A1 Lellouche, Francois A2 Tobin, Martin J. SR Print(0) ID 57062930 T1 Chapter 8. Pressure-Support Ventilation T2 Principles and Practice of Mechanical Ventilation, 3e YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-173626-8 LK accessmedicine.mhmedical.com/content.aspx?aid=57062930 RD 2024/04/25 AB Pressure-support ventilation (PSV) is a mode of partial ventilator support. Such modes are widely used in intensive care units (ICUs) because most ventilated patients (unless deeply sedated) have preserved respiratory drive. The use of these modes helps to reduce need for sedation, an important issue in the ICU,1,2 and potentially prevents disuse atrophy of the respiratory muscles that can result from controlled ventilation.3,4 This preventive effect has been shown experimentally with different modes of partial support.3,5 Finally, partial support may facilitate both the screening process for detecting patients able to breathe spontaneously as well as the weaning of patients with prolonged or difficult weaning.6 An ideal mode of partial support should be able to supply both full ventilator support and optimal support during weaning; optimize patient–ventilator synchronization and comfort while reducing the need for sedation and the risk of cardiovascular consequences; and, if possible, facilitate or reduce the duration of the weaning. PSV meets several of these requirements, at least partially, as discussed in this chapter. PSV also has limitations, which are delineated. One important limitation is that overassistance of the patient can be easily reached and improvement in the delivery of the optimal PSV level continues as a field of research.