RT Book, Section A1 Kemp, Walter L. A1 Burns, Dennis K. A1 Brown, Travis G. SR Print(0) ID 57055487 T1 Chapter 18. Endocrine Pathology T2 Pathology: The Big Picture YR 2008 FD 2008 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-147748-2 LK accessmedicine.mhmedical.com/content.aspx?aid=57055487 RD 2024/10/08 AB In general, most endocrine pathology involves either the overproduction or the underproduction of a hormone. Overproduction of a given hormone may be caused by hyperplasia of the organ that produces the hormone, by a neoplastic process, or by some combination of the two processes. Underproduction of a given hormone, in contrast, may be caused by either destruction of the gland that produces the hormone or by conditions that deprive an endocrine organ of its normal trophic influence.