RT Book, Section A1 Krakow, Elizabeth F. A1 Fraser, Graeme A2 McKean, Sylvia C. A2 Ross, John J. A2 Dressler, Daniel D. A2 Brotman, Daniel J. A2 Ginsberg, Jeffrey S. SR Print(0) ID 56208532 T1 Chapter 179. Hematologic Malignancies T2 Principles and Practice of Hospital Medicine YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-160389-8 LK accessmedicine.mhmedical.com/content.aspx?aid=56208532 RD 2024/04/19 AB What are the “classic” clinical and basic laboratory features of each of the common hematologic malignancies? (“How do I prove the diagnosis?”)What is the natural history of each disease entity without therapy?What is the goal of treatment for each disease entity (cure, prolongation of survival, or purely palliation)?Which modalities may be employed for each disease entity (chemotherapy, immunotherapy, radiation, stem cell transplant)?What is the prognosis with therapy? How can the prognosis estimate be refined?What needs to be done to prepare the patient for therapy (to communicate risks and benefits and to reduce toxicity)?How do we assess the response?How do we monitor the patient after completion of therapy, both early on (for relapse) and later (for delayed toxicities of therapy)?