RT Book, Section A1 Cooper, Zara A1 Ashley, Stanley A2 McKean, Sylvia C. A2 Ross, John J. A2 Dressler, Daniel D. A2 Brotman, Daniel J. A2 Ginsberg, Jeffrey S. SR Print(0) ID 56194155 T1 Chapter 45. Perioperative Hemostasis T2 Principles and Practice of Hospital Medicine YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-160389-8 LK accessmedicine.mhmedical.com/content.aspx?aid=56194155 RD 2024/04/18 AB Postoperative bleeding is a dreaded surgical complication. More often than not you will hear, “It was dry when we closed…” as your surgical colleagues struggle to identify the source. Risk factors include trauma, coagulopathy, or factor deficiency, which may be congenital or acquired from malnutrition, antibiotic use, or liver disease. Hospitalized patients are commonly anticoagulated prior to surgery. Patients at risk should have a preoperative evaluation including a complete blood count, liver function tests, prothrombin time, activated partial prothrombin time, and international normalized ratio (Figure 45-1). Patients with platelet dysfunction from aspirin, antiplatelet agents, or uremia are also at increased risk of postoperative hemorrhage.