RT Book, Section A1 Cevasco, Marisa A1 Ashley, Stanley A1 Cooper, Zara A2 McKean, Sylvia C. A2 Ross, John J. A2 Dressler, Daniel D. A2 Brotman, Daniel J. A2 Ginsberg, Jeffrey S. SR Print(0) ID 56194092 T1 Chapter 44. Physiologic Response to Surgery T2 Principles and Practice of Hospital Medicine YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-160389-8 LK accessmedicine.mhmedical.com/content.aspx?aid=56194092 RD 2024/04/16 AB Since 1932, when Cuthbertson first described the systemic response to lower-limb injury, our understanding of surgical physiology has grown significantly, resulting in improved perioperative management, decreased complications, more efficacious analgesia, and faster recovery times. Better control of the sympathoadrenal pathway, endocrine response, and fluid management results in less patient fatigue, shorter functional recovery, and decreased hospital stays. In this chapter we will review the surgical stress response, fluid and electrolyte balance, and organ-specific responses to surgery.