RT Book, Section
A1 Vujevich, Justin J.
A1 Goldberg, Leonard H.
A2 Goldsmith, Lowell A.
A2 Katz, Stephen I.
A2 Gilchrest, Barbara A.
A2 Paller, Amy S.
A2 Leffell, David J.
A2 Wolff, Klaus
SR Print(0)
ID 56106633
T1 Chapter 246. Cryosurgery and Electrosurgery
T2 Fitzpatrick's Dermatology in General Medicine, 8e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-166904-7
LK accessmedicine.mhmedical.com/content.aspx?aid=56106633
RD 2024/04/19
AB Cryosurgery  refers  to  the  use  of  extreme  cold  to  destroy  cells  of  abnormal  or  diseased  tissue.  The  earliest  use  of  a  cold  refrigerant  in  medicine  is  attributed  to  White,  a  New  York  dermatologist,  in  1899.1,2  Using  a  cotton-tipped  applicator  dipped  into  liquefied  air,  he  successfully  treated  warts,  nevi,  and  precancerous  and  cancerous  lesions.  In  1907,  Whitehouse,  another  New  York  dermatologist,  reported  the  utilization  of  the  spray  method  in  the  cryosurgical  treatment  of  skin  cancers.3