RT Book, Section A1 Cafardi, Jennifer A. A1 Pollack, Brian P. A1 Elmets, Craig A. A2 Goldsmith, Lowell A. A2 Katz, Stephen I. A2 Gilchrest, Barbara A. A2 Paller, Amy S. A2 Leffell, David J. A2 Wolff, Klaus SR Print(0) ID 56103273 T1 Chapter 237. Phototherapy T2 Fitzpatrick's Dermatology in General Medicine, 8e YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-166904-7 LK accessmedicine.mhmedical.com/content.aspx?aid=56103273 RD 2024/09/08 AB |PrintPhototherapy at a GlancePhototherapeutic devices have varying properties with respect to depth of UV penetration into the skin, effects on cells and molecules, potency, side effects and diseases in which they are most effective.In use today are narrowband and broadband UVB, UVA as part of psoralen photochemotherapy (PUVA), UVA1 and targeted phototherapy (excimer lasers and nonlaser monochromatic excimer light sources).Narrowband UVB is currently preferred to treat psoriasis, other inflammatory skin diseases, and vitiligo.Psoralen-UVA photochemotherapy (PUVA) combines oral or topical psoralen compounds with UVA light sources. Its main uses are treatment of cutaneous T-cell lymphoma, vitiligo, and psoriasis that is resistant to narrowband UVB.UVA1 phototherapy is particularly effective for sclerotic skin diseases such as localized scleroderma, acute flares of atopic dermatitis and urticaria pigmentosa.Targeted phototherapy allowing relatively high UV doses to be delivered to diseased skin while sparing normal skin.