RT Book, Section
A1 Callen, Jeffrey P.
A2 Goldsmith, Lowell A.
A2 Katz, Stephen I.
A2 Gilchrest, Barbara A.
A2 Paller, Amy S.
A2 Leffell, David J.
A2 Wolff, Klaus
SR Print(0)
ID 56102014
T1 Chapter 233. Immunosuppressive and Immunomodulatory Drugs
T2 Fitzpatrick's Dermatology in General Medicine, 8e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-166904-7
LK accessmedicine.mhmedical.com/content.aspx?aid=56102014
RD 2024/04/19
AB |PrintImmunosuppressive  and  Immunomodulatory  Drugs  at  a  GlanceThe  main  goals  in  immunotherapy  are  safety  and  effectiveness.Unlike  immunomodulators,  immunosuppressive  drugs  are  all  characterized  by  a  narrow  therapeutic  window  requiring  precise  dosing  and  close  side-effect  monitoring.The  highest  level  of  safety  and  effectiveness  in  immunotherapy  therapy  is  currently  accomplished  by  the  use  of  combined  regimens.An  additive  or  synergistic  combined  immunotherapeutic  regimen  allows  significant  reduction  of  dose-dependent  drug  side  effects  maintaining  or  improving  the  effectiveness,  respectively.A  comprehensive  knowledge  of  the  pathophysiology  of  the  treating  disease  as  well  as  of  the  pharmacokinetics  and  pharmacodynamics  concepts  is  crucial  for  delineating  the  most  effective  and  safest  therapeutic  regimens.