RT Book, Section A1 Wood, Robert A. A2 Goldsmith, Lowell A. A2 Katz, Stephen I. A2 Gilchrest, Barbara A. A2 Paller, Amy S. A2 Leffell, David J. A2 Wolff, Klaus SR Print(0) ID 56100245 T1 Chapter 229. Antihistamines T2 Fitzpatrick's Dermatology in General Medicine, 8e YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-166904-7 LK accessmedicine.mhmedical.com/content.aspx?aid=56100245 RD 2024/03/28 AB |PrintAntihistamines at a GlanceH1 are first-line therapy for chronic idiopathic and physical urticarias.H1 may be useful in treating other conditions with histamine-driven pruritus.Limited evidence supports the use of H1 in treatment of atopic dermatitis.Certain special patient populations, including children, the elderly, and patients with renal or hepatic impairment, may require dosage adjustments when using H1 antihistamines.The use of H1 is contraindicated in patients who have narrow angle glaucoma or who are also taking monoamine oxidase inhibitors.H2 antihistamines may be a useful adjunct to H1 antihistamine therapy in refractory cases of chronic idiopathic urticaria/angioedema and pruritus.