RT Book, Section
A1 Esparza, Edward M.
A1 Sidbury, Robert
A2 Goldsmith, Lowell A.
A2 Katz, Stephen I.
A2 Gilchrest, Barbara A.
A2 Paller, Amy S.
A2 Leffell, David J.
A2 Wolff, Klaus
SR Print(0)
ID 56097730
T1 Chapter 221. Topical Immunomodulators
T2 Fitzpatrick's Dermatology in General Medicine, 8e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-166904-7
LK accessmedicine.mhmedical.com/content.aspx?aid=56097730
RD 2024/10/15
AB Topical  immunomodulators  are  nonsteroidal  agents  that  target  the  immune  system  for  therapeutic  effect  in  the  skin.  The  macrolactams,  pimecrolimus  and  tacrolimus,  act  as  anti-inflammatory  agents  by  binding  immunophilin  and  inhibiting  cytokine  production.  The  imidazoquinoline  amine,  imiquimod,  induces  interferon  (IFN)  production  and  enhances  immune  responses,  although  several  more  potent  analogs  are  under  clinical  investigation.