RT Book, Section
A1 Lautenschlager, Stephan
A2 Goldsmith, Lowell A.
A2 Katz, Stephen I.
A2 Gilchrest, Barbara A.
A2 Paller, Amy S.
A2 Leffell, David J.
A2 Wolff, Klaus
SR Print(0)
ID 56091426
T1 Chapter 202. Chancroid
T2 Fitzpatrick's Dermatology in General Medicine, 8e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-166904-7
LK accessmedicine.mhmedical.com/content.aspx?aid=56091426
RD 2024/04/19
AB |PrintChancroid  at  a  GlanceA  sexually  transmitted  acute  ulcerative  disease  usually  localized  at  the  anogenital  area  and  often  associated  with  inguinal  adenitis  or  bubo.Haemophilus  ducreyi—a  Gram-negative,  facultative  anaerobic  coccobacillus—is  the  causative  agent.Although  the  number  of  cases  is  decreasing  overall,  chancroid  is  still  common  in  many  developing  countries  (Africa,  the  Caribbean  Islands,  and  Southwest  Asia).Painful,  soft  ulcers  with  ragged  undermined  margins  develop  1–2  weeks  after  inoculation  (usually  prepuce  and  frenulum  in  men  and  vulva,  cervix,  and  perianal  area  in  women).Nonsexual  transmission  has  been  reported  recently.Chancroid  facilitates  the  transmission  of  HIV.Laboratory  culture  of  H.  ducreyi  is  problematic,  but  greater  sensitivity  can  be  expected  by  DNA  amplification  methods,  which  are  currently  not  routinely  available.Azithromycin  and  Ceftriaxone  are  recommended  as  single-dose  treatment,  enhancing  compliance.