RT Book, Section
A1 Kopp, Sandra A.
A1 Halpern, Analisa V.
A1 Green, Justin J.
A1 Heymann, Warren R.
A2 Goldsmith, Lowell A.
A2 Katz, Stephen I.
A2 Gilchrest, Barbara A.
A2 Paller, Amy S.
A2 Leffell, David J.
A2 Wolff, Klaus
SR Print(0)
ID 56090327
T1 Chapter 199. The Rickettsioses, Ehrlichioses, and Anaplasmoses
T2 Fitzpatrick's Dermatology in General Medicine, 8e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-166904-7
LK accessmedicine.mhmedical.com/content.aspx?aid=56090327
RD 2024/04/24
AB |PrintRICKETTSIAL,  EHRLICHIAL,  AND  Anaplasma  INFECTIONS  AT  A  GLANCERickettsiae  primarily  target  vascular  endothelial  cells,  causing  febrile  illness  and  rash  in  the  mammalian  host.Transmission  is  predominantly  via  tick  bites,  with  certain  pathogens  transmitted  by  human  body  lice  and  mites.Fever,  headache,  myalgia,  and  malaise  are  common  to  rickettsial,  ehrlichial,  and  Anaplasma  infections;  rash  is  common  in  rickettsial  disease,  occasional  in  ehrlichial  infection,  and  rare  in  anaplasmosis.The  early  signs  and  symptoms  of  infection  are  often  nonspecific  and  can  mimic  self-limited  viral  illnesses  or  other  life-threatening  illnesses.Early  empiric  treatment  with  doxycycline  should  be  considered  in  highly  suspicious  cases  until  rickettsial  infection  is  definitively  ruled  out,  as  delayed  treatment  can  lead  to  severe  sequelae  and  high  mortality  rates.