RT Book, Section
A1 Uihlein, Lily Changchien
A1 Saavedra, Arturo P.
A1 Johnson, Richard Allen
A2 Goldsmith, Lowell A.
A2 Katz, Stephen I.
A2 Gilchrest, Barbara A.
A2 Paller, Amy S.
A2 Leffell, David J.
A2 Wolff, Klaus
SR Print(0)
ID 56089773
T1 Chapter 198. Cutaneous Manifestations of Human Immunodeficiency Virus Disease
T2 Fitzpatrick's Dermatology in General Medicine, 8e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-166904-7
LK accessmedicine.mhmedical.com/content.aspx?aid=56089773
RD 2024/04/23
AB |PrintHuman  Immunodeficiency  Virus  (HIV)  Infection  and  Acquired  Immune-Deficiency  Syndrome  (AIDS)  at  a  GlanceAs  of  2008,  more  than  30  million  people  were  living  with  HIV  infection/AIDS.HIV-1  and  HIV-2  are  human  lymphotropic  retroviruses  that  principally  infect  CD4+  T  lymphocytes  and  CD4+  cells  of  monocytic  lineage.An  individual  is  deemed  to  have  AIDS  if  he  or  she  is  HIV-seropositive  with  a  CD4+  T  cell  count  <200/μL,  a  CD4+  T  cell  percentage  <14,  or  any  of  several  diseases  deemed  to  be  indicative  of  a  severe  defect  in  cell-mediated  immunity.The  broad  and  diverse  spectrum  of  dermatologic  disease  in  HIV  infection/AIDS  includes  inflammatory,  infectious,  neoplastic,  and  medication-related  disorders.Specific  stages  of  HIV  disease  (acute  HIV  syndrome,  immune  reconstitution,  clinically  latent  disease,  and  advanced  disease)  tend  to  be  associated  with  different  dermatologic  disorders.Dermatologic  disease  may  help  to  estimate  the  level  of  immunosuppression  in  HIV  infection/AIDS,  particularly  in  resource-limited  settings.As  there  are  many  dermatologic  disorders  that  are  seen  in  HIV  infection/AIDS,  this  chapter  focuses  on  those  diseases  that  are  the  most  closely  associated.