RT Book, Section A1 Piggott, Caroline A1 Friedlander, Sheila Fallon A1 Tom, Wynnis A2 Goldsmith, Lowell A. A2 Katz, Stephen I. A2 Gilchrest, Barbara A. A2 Paller, Amy S. A2 Leffell, David J. A2 Wolff, Klaus SR Print(0) ID 56088919 T1 Chapter 195. Poxvirus Infections T2 Fitzpatrick's Dermatology in General Medicine, 8e YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-166904-7 LK accessmedicine.mhmedical.com/content.aspx?aid=56088919 RD 2024/04/18 AB |PrintPoxviruses at a GlancePoxviruses are the largest animal viruses; they can cause disease of varying severity in humans.Smallpox is the only poxvirus for which humans are the sole reservoir, which allowed its eradication.The smallpox vaccine virus, vaccinia, has its own adverse effects.Monkeypox is a zoonotic infection endemic in Africa, but it has recently appeared in the Western Hemisphere.Milker's nodule and orf mainly cause localized cutaneous infections.Molluscum contagiosum is generally a benign cutaneous disease most frequently seen in children and immunocompromised individuals.Histopathologic features of poxviral cutaneous lesions include the presence of intracytoplasmic eosinophilic inclusion bodies.