RT Book, Section
A1 Lee, Delphine J.
A1 Rea, Thomas H.
A1 Modlin, Robert L.
A2 Goldsmith, Lowell A.
A2 Katz, Stephen I.
A2 Gilchrest, Barbara A.
A2 Paller, Amy S.
A2 Leffell, David J.
A2 Wolff, Klaus
SR Print(0)
ID 56084826
T1 Chapter 186. Leprosy
T2 Fitzpatrick's Dermatology in General Medicine, 8e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-166904-7
LK accessmedicine.mhmedical.com/content.aspx?aid=56084826
RD 2023/06/07
AB |PrintLeprosy  at  a  GlanceDefinition:  a  chronic  granulomatous  infection  and  caused  by  M.  leprae.Involvement:  affecting  primarily  skin  and  nerves.Diagnosis:  acid-fast  bacilli  in  tissue  or  classic  peripheral  nerve  abnormality.Incidence:  approximately  250,000–500,000  new  cases  yearly,  worldwide.Long-term  morbidity:  despite  curative  antibacterial  treatment,  one-quarter  to  one-third  of  patients  will  have  a  debilitating  and  permanent  neurological  deficit.A  clinical  challenge:  diverse  manifestations  result  from  a  granulomatous  spectrum,  and  are  further  increased  by  superimposed,  reactional  states.An  immunologic  opportunity:  an  exemplary  model  for  the  understanding  of  cell-mediated  immunity  in  humans.