RT Book, Section A1 Illei, Gabor A1 Danielides, Stamatina A2 Goldsmith, Lowell A. A2 Katz, Stephen I. A2 Gilchrest, Barbara A. A2 Paller, Amy S. A2 Leffell, David J. A2 Wolff, Klaus SR Print(0) ID 56077702 T1 Chapter 161. Sjögren's Syndrome T2 Fitzpatrick's Dermatology in General Medicine, 8e YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-166904-7 LK accessmedicine.mhmedical.com/content.aspx?aid=56077702 RD 2024/03/28 AB |PrintSjögren's Syndrome at a GlanceChronic autoimmune disease characterized by chronic inflammation involving the exocrine glands.Salivary and lachrymal glands are predominantly affected leading to dry mouth and dry eyes.May occur alone (primary Sjögren's syndrome), or may coexist with other systemic connective tissue disorders (secondary Sjögren's syndrome).Systemic manifestations, such as fatigue, arthritis, vasculitis, interstitial pulmonary disease, peripheral or central neuropathy, and autonomic nervous dysfunction may accompany glandular involvement.Patients with systemic manifestations are at higher risk of lymphoma.Treatment of sicca symptoms is mainly symptomatic, whereas management of extraglandular manifestations is similar to other autoimmune diseases.