RT Book, Section
A1 Piette, Warren W.
A2 Goldsmith, Lowell A.
A2 Katz, Stephen I.
A2 Gilchrest, Barbara A.
A2 Paller, Amy S.
A2 Leffell, David J.
A2 Wolff, Klaus
SR Print(0)
ID 56071604
T1 Chapter 144. Hematologic Diseases
T2 Fitzpatrick's Dermatology in General Medicine, 8e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-166904-7
LK accessmedicine.mhmedical.com/content.aspx?aid=56071604
RD 2024/04/24
AB |PrintHematologic  Diseases  at  a  GlanceMucocutaneous  changes  (i.e.,  pallor,  jaundice,  flushing,  erythema,  and  cyanosis)  often  predict  underlying  hematologic  pathology.Anemia  is  best  differentiated  by  mean  corpuscular  volume  value.Megaloblastic  anemia  of  vitamin  B12  deficiency  is  distinguished  from  folate  deficiency  by  lack  of  neurologic  signs  in  folate  deficiency.Carcinoid  tumor  results  in  flushing,  typically  for  10  minutes  or  less;  in  comparison,  flushing  from  mastocytosis  lasts  30  minutes  or  more.Polycythemia  vera  presents  with  acrocyanosis,  aquagenic  pruritus,  urticaria,  Sweet  syndrome,  and  purpura.The  morphologic  diagnosis  of  purpura  begins  with  three  Ps:  (1)  is  the  lesion  purpuric,  (2)  is  it  primary,  and  (3)  is  it  palpable?Leukemia  cutis  is  a  localized  or  disseminated  skin  infiltration  by  leukemic  cells.  It  is  a  sign  of  dissemination  or  systemic  disease  or  relapsing  leukemia.