RT Book, Section A1 Brenn, Thomas A2 Goldsmith, Lowell A. A2 Katz, Stephen I. A2 Gilchrest, Barbara A. A2 Paller, Amy S. A2 Leffell, David J. A2 Wolff, Klaus SR Print(0) ID 56064301 T1 Chapter 129. Neoplasms of Subcutaneous Fat T2 Fitzpatrick's Dermatology in General Medicine, 8e YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-166904-7 LK accessmedicine.mhmedical.com/content.aspx?aid=56064301 RD 2024/10/04 AB |PrintNeoplasms of Subcutaneous Fat at a GlanceAdipocyte tumors are the most frequently encountered group of mesenchymal neoplasms. This is due to the high prevalence of lipoma and angiolipoma.Tumors range from entirely benign neoplasms (e.g., lipomas) to those of intermediate malignant potential with risk for local recurrence (e.g., atypical lipomatous tumor) to high-grade pleomorphic sarcomas (e.g., pleomorphic liposarcoma).Although liposarcoma is the single most frequently encountered sarcoma, the large majority of adipocyte tumors are benign.The clinical presentation of adipocyte tumors is generally nonspecific.Most adipocyte tumors show distinctive cytogenetic abnormalities that may be of diagnostic value.Treatment is surgical excision. Adjuvant radiation therapy and/or chemotherapy may be of benefit for treatment of malignant tumors that are not amenable to complete excision or in cases of advanced disease.