RT Book, Section
A1 Becker, Jürgen C.
A1 Liegl-Atzwanger, Bernadette
A1 Ugurel, Selma
A2 Goldsmith, Lowell A.
A2 Katz, Stephen I.
A2 Gilchrest, Barbara A.
A2 Paller, Amy S.
A2 Leffell, David J.
A2 Wolff, Klaus
SR Print(0)
ID 56063111
T1 Chapter 125. Malignant Fibrous, Fibrohistiocytic, and Histiocytic Tumors of the Dermis
T2 Fitzpatrick's Dermatology in General Medicine, 8e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-166904-7
LK accessmedicine.mhmedical.com/content.aspx?aid=56063111
RD 2024/04/20
AB |PrintMalignant  Fibrous  Dermal  Tumors  at  a  GlanceA  group  of  uncommon  and  rare  cutaneous  tumors  with  varying  degrees  of  malignant  potential.Includes  dermatofibrosarcoma  protuberans  (DFSP),  atypical  fibroxanthoma  (AFX),  desmoids  tumor,  myxofibrosarcoma  (MFS),  undifferentiated  pleomorphic  sarcomas  (UPS),  and  epithelioid  sarcoma  (ES).Diagnosis  is  made  by  biopsy.DFSP  is  a  locally  aggressive  tumor  with  a  high  rate  of  local  recurrence  with  rare  metastases.AFX  is  an  intermediate-grade  neoplasm  that  usually  arises  on  sun-damaged  skin  in  the  eighth  decade.Desmoid  tumors  are  slowly  growing  tumors  arising  from  the  muscular  aponeurosis  that  have  been  associated  with  a  history  of  trauma  or  an  operation;  thus,  women  undergoing  cesarean  sections  are  at  greater  risk.MFS  represent  a  spectrum  of  malignant  myxoid  tumors  of  fibroblastic  origin  that  exhibit  a  range  of  clinical  and  histopathologic  features.UPS  is  almost  never  a  cutaneous  tumor.ES  is  a  rare,  highly  aggressive  tumor  that  classically  presents  on  the  hands  and  fingers  of  young  males,  which  can  mimic  nonneoplastic  inflammatory  lesions.