RT Book, Section
A1 Fealey, Robert D.
A1 Hebert, Adelaide A.
A2 Goldsmith, Lowell A.
A2 Katz, Stephen I.
A2 Gilchrest, Barbara A.
A2 Paller, Amy S.
A2 Leffell, David J.
A2 Wolff, Klaus
SR Print(0)
ID 56048007
T1 Chapter 84. Disorders of the Eccrine Sweat Glands and Sweating
T2 Fitzpatrick's Dermatology in General Medicine, 8e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-166904-7
LK accessmedicine.mhmedical.com/content.aspx?aid=56048007
RD 2024/09/11
AB |PrintHyperhidrosis  and  Anhidrosis  at  a  GlancePrimary  focal  (essential)  hyperhidrosis:  Affects  over  6  million  young  people  worldwide.Excessive  palmar  sweating  affects  quality  of  life.Effective  treatments  (stratified  to  match  the  severity)  include  topical  agents,  iontophoresis,  oral  anticholinergics,  and  botulinum  toxin.Endoscopic  thoracic  sympathetic  surgery  is  a  last-line  choice  for  severe  hyperhidrosis.Localized,  large  areas  of  hyperhidrosis  may  be  compensatory.  Clue  to  loss  of  sweating  elsewhere.Determine  location  of  sudomotor  lesion  and  underlying  cause  by  thermoregulatory  sweat  testing  combined  with  direct  and  axon  reflex  sweat  evaluation.Patterns  of  anhidrosis  provide  objective  evidence  of  small  nerve  fiber  and/or  eccrine  gland  involvement  in  many  neurologic  and  dermatologic  disorders.Analysis  of  sweat  composition  continues  to  be  diagnostic  in  cystic  fibrosis.Determination  of  sweat-derived  antimicrobial  peptides  may  provide  evidence  of  impaired  innate  defense  in  skin  disorders  such  as  atopic  dermatitis  and  neutrophilic  eccrine  hidradenitis.