RT Book, Section
A1 Woo, Sook-Bin
A2 Goldsmith, Lowell A.
A2 Katz, Stephen I.
A2 Gilchrest, Barbara A.
A2 Paller, Amy S.
A2 Leffell, David J.
A2 Wolff, Klaus
SR Print(0)
ID 56044576
T1 Chapter 76. Biology and Pathology of the Oral Cavity
T2 Fitzpatrick's Dermatology in General Medicine, 8e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-166904-7
LK accessmedicine.mhmedical.com/content.aspx?aid=56044576
RD 2024/09/20
AB |PrintOral  Mucosal  Disease  at  a  GlanceIdiopathic  recurrent  aphthous  ulcers  affect  15%–20%  of  the  population;  severe  cases  can  be  debilitating.Oral  ulcers  may  also  be  associated  with  Crohn  disease  and  other  gastrointestinal  disorders  or  due  to  herpes  simplex,  other  viral  infections,  vasculitis,  or  other  autoimmune  disorders.Candidiasis  of  the  oral  cavity  is  common  and  painful.  Predisposing  factors  include  immunosuppression,  hyposalivation,  and  use  of  steroids  or  antibiotics.Hair  leukoplakia  is  due  to  Epstein–Barr  viral  infection  and  may  be  the  presenting  sign  of  HIV/AIDS.Oral  lichen  planus  (LP)  and  lichenoid  reactions  affect  1%–2%  of  the  population  and  are  the  most  common  cause  of  desquamative  gingivitis;  LP  probably  reflects  a  hypersensitivity  response  to  endogenous  or  exogenous  antigens.Leukoplakia  is  a  premalignant  condition  associated  with  smoking  and/or  alcohol  ingestion  that  must  be  distinguished  from  LP  and  benign  frictional  keratoses.Bullous  diseases  that  affect  the  mouth  include  pemphigus,  pemphigoid,  and  lupus  erythematous.Intraoral  pigmented  lesions  include  nevi,  postinflammatory  hyperpigmentation,  drug  reactions,  tattoos,  and  rarely  melanoma.